Human GLP1R Full Length Protein (VLP), Unconjugated 20 ug
Biozol Catalog Number:
ABS-GLR-H52P3-20UG
Supplier Catalog Number:
GLR-H52P3-20ug
Alternative Catalog Number:
ABS-GLR-H52P3-20UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
GLP1R (GlucagonLike Peptide1 Receptor) is a type of Gproteincoupled receptor (GPCR) that plays a crucial role in metabolic regulation, and its specific ligand is glucagonlike peptide1 (GLP1). The binding of GLP1 to GLP1R induces a conformational change in the receptor, subsequently triggering downstream signaling cascades. These cascades further activate adenylyl cyclase, ultimately leading to an increase in intracellular cyclic adenosine monophosphate (cAMP) levels. Studies have demonstrated that GLP1R can regulate insulin secretion in response to GLP1 through the aforementioned pathway (By similarity), which is of great significance for maintaining systemic glucose homeostasis. - Proteine/Peptide
Immobilized Human GLP1R Full Length Protein (VLP) (Cat. No. GLR-H52P3) at 5 µg/mL (100 µL/well) can bind Anti-GLP1R antibody, Human IgG2 with a linear range of 0.05-3 ng/mL (QC tested).
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