Human GPR75 Full Length Protein (VLP), Unconjugated 100 ug
Biozol Catalog Number:
ABS-GP5-H52P3-100UG
Supplier Catalog Number:
GP5-H52P3-100ug
Alternative Catalog Number:
ABS-GP5-H52P3-100UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
G proteincoupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor. - Proteine/Peptide