Human Osteoactivin / GPNMB Protein, His Tag, Unconjugated

Product Overview

• Article Name: Human Osteoactivin / GPNMB Protein, His Tag, Unconjugated
• Biozol Catalog Number: ABS-GPB-H5229-1MG
• Supplier Catalog Number: GPB-H5229-1mg
• Alternative Catalog Number: ABS-GPB-H5229-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Transmembrane glycoprotein NMB (GPNMB) is also known as Transmembrane glycoprotein HGFIN, DCHIL and Osteoactivin (OA), which belongs to the PMEL/NMB family. GPNMB contains one PKD domain. GPNMB is a transmembrane glycoprotein that is upregulated in various cancer cells, including in glioblastoma multiforme and is expressed in many melanoma cells, as well as in tissue macrophages. GPNMB protein acts as a downstream mediator of BMP2 effects on osteoblast differentiation and function. GPNMB participates in bone mineralization, and functions as a negative regulator of inflammation in macrophages. - Proteine/Peptide

Product Properties

• Molecular Weight: 53.4 kDa
• Tag: C-10*His
• NCBI: 32783
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: Osteoactivin

Images

Human Osteoactivin, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.