Mouse GUCY2C / Guanylyl cyclase C Protein, His Tag (MALS verified), Unconjugated, Human

Product Overview

• Article Name: Mouse GUCY2C / Guanylyl cyclase C Protein, His Tag (MALS verified), Unconjugated, Human
• Biozol Catalog Number: ABS-GUC-M52H3-1MG
• Supplier Catalog Number: GUC-M52H3-1mg
• Alternative Catalog Number: ABS-GUC-M52H3-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Mouse
• Conjugation: Unconjugated

Product Description

GUCY2C (Guanylyl Cyclase C), also known as heatstable enterotoxin receptor, is a type I transmembrane protein of the guanylate cyclase (gc) family that signal by producing cGMP. Guanylate cyclase C (GUCY2C) and its hormones guanylin and uroguanylin have recently emerged as one paracrine axis defending intestinal mucosal integrity against mutational, chemical, and inflammatory injury. GUCY2C murine CART cells recognized and killed human colorectal cancer cells endogenously expressing GUCY2C. Thus, we have identified a human GUCY2Cspecific CART cell therapy approach that may be developed for the treatment of GUCY2Cexpressing metastatic colorectal cancer. - Proteine/Peptide

Product Properties

• Molecular Weight: 49.0 kDa
• Tag: C-10*His
• NCBI: 3
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: GUCY2C

Images

Mouse GUCY2C, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.