Biotinylated Mouse H-2Kd&B2M&InsB (LYLVCGERL) Complex Protein (Monomer, MALS verified), Human

Product Overview

• Article Name: Biotinylated Mouse H-2Kd&B2M&InsB (LYLVCGERL) Complex Protein (Monomer, MALS verified), Human
• Biozol Catalog Number: ABS-H2B-M82E3-25UG
• Supplier Catalog Number: H2B-M82E3-25ug
• Alternative Catalog Number: ABS-H2B-M82E3-25UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Mouse
• Conjugation: Biotin

Product Description

The peptide LYLVCGERL, derived from mouse insulin B chain (InsB), is presented by the H2Kd/beta2microglobulin (beta2m) complex. This complex is a central autoantigen in the nonobese diabetic (NOD) mouse model of type 1 diabetes. Recognition of this peptideMHC complex by autoreactive CD8 T cells is a critical early event in the destruction of insulinproducing pancreatic beta cells, making it a fundamental target for studying autoimmune diabetes pathogenesis and tolerance mechanisms. - Proteine/Peptide

Product Properties

• Molecular Weight: 40.0 kDa and 15.6 kDa
• Tag: C-10*His & C-Avi
• NCBI: 01902
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: H-2Kd & B2M & InsB (LYLVCGERL)

Images

Biotinylated Mouse H-2Kd&B2M&InsB (LYLVCGERL) Complex Protein on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.