Biotinylated Human HLA-A*02:01&B2M&SSX-2 (KASEKIFYV) Complex Protein (Monomer, MALS verified)

Catalog Number: ABS-HL2-H82ES-200UG
Article Name: Biotinylated Human HLA-A*02:01&B2M&SSX-2 (KASEKIFYV) Complex Protein (Monomer, MALS verified)
Biozol Catalog Number: ABS-HL2-H82ES-200UG
Supplier Catalog Number: HL2-H82Es-200ug
Alternative Catalog Number: ABS-HL2-H82ES-200UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Biotin
The peptide KASEKIFYV, derived from the cancertestis antigen SSX2, is presented by the HLAA*02:01/beta2microglobulin (beta2m) complex. This peptideMHC complex is recognized as a tumorassociated antigen and can elicit specific cytotoxic T lymphocyte (CTL) responses. Its presentation on certain tumor cells makes it a potential target for cancer immunotherapy, particularly in cancers where SSX2 is aberrantly expressed, such as melanoma, synovial sarcoma, and some carcinomas. - Proteine/Peptide
Molecular Weight: 36.3 kDa and 11.7 kDa
Tag: C-10*His & C-Avi
NCBI: 59606
Buffer: PBS, pH7.4
Purity: 90%
Form: Powder
Target: HLA-A*0201 & B2M & SSX-2 (KASEKIFYV)
Immobilized Biotinylated Human HLA-A*02:01&B2M&SSX-2 (KASEKIFYV) Complex Protein (Cat. No. HL2-H82Es) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Anti-HLA class I Antibody, Human IgG1 (W6/32) with a linear range of 0.1-3 ng/mL (QC tested).
Immobilized Biotinylated Human HLA-A*02:01&B2M&SSX-2 (KASEKIFYV) Complex Protein (Cat. No. HL2-H82Es) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Anti-B2M Antibody, Human IgG1 with a linear range of 0.1-3 ng/mL (Routinely tested).
Biotinylated Human HLA-A*02:01&B2M&SSX-2 (KASEKIFYV) Complex Protein on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.