Biotinylated Human HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Complex Protein (Monomer, MALS verified)

Catalog Number: ABS-HLN-H82E7-200UG
Article Name: Biotinylated Human HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Complex Protein (Monomer, MALS verified)
Biozol Catalog Number: ABS-HLN-H82E7-200UG
Supplier Catalog Number: HLN-H82E7-200ug
Alternative Catalog Number: ABS-HLN-H82E7-200UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Biotin
The HLAA*02:01&B2M&Survivin (LTLGEFLKL) complex is a key antigenpresenting complex in the immune system. HLAA*02:01, a major histocompatibility complex (MHC) class I molecule, forms a stable heterodimer with beta2microglobulin (B2M). Subsequently, this dimer binds to the Survivinderived peptide LTLGEFLKL-a specific epitope of Survivin, an antiapoptotic protein overexpressed in various tumors. This complex is critical for activating cytotoxic T lymphocytes (CTLs), enabling the immune system to recognize and eliminate tumor cells expressing Survivin. - Proteine/Peptide
Molecular Weight: 36.3 kDa and 11.7 kDa
Tag: C-10*His & C-Avi
NCBI: 59606
Buffer: PBS, pH7.4
Purity: 90%
Form: Powder
Target: HLA-A*0201 & B2M & Survivin (LTLGEFLKL)
Immobilized Anti-HLA class I Antibody, Human IgG1 (W6/32) at 1 µg/mL (100 µL/well) can bind Biotinylated Human HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Complex Protein (Cat. No. HLN-H82E7) with a linear range of 0.2-4 ng/mL (QC tested).
Immobilized Anti-B2M Antibody, Human IgG1 at 1 µg/mL (100 µL/well) can bind Biotinylated Human HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Complex Protein (Cat. No. HLN-H82E7) with a linear range of 0.1-4 ng/mL (Routinely tested).
Biotinylated Human HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Complex Protein on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.