Biotinylated Human HLA-A*11:01&B2M&KRASG12R (VVVGARGVGK) Complex Protein (Monomer, MALS verified)

Product Overview

• Article Name: Biotinylated Human HLA-A*11:01&B2M&KRASG12R (VVVGARGVGK) Complex Protein (Monomer, MALS verified)
• Biozol Catalog Number: ABS-HLR-H82E2-200UG
• Supplier Catalog Number: HLR-H82E2-200ug
• Alternative Catalog Number: ABS-HLR-H82E2-200UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

The peptide VVVGARGVGK, derived from the KRAS G12R mutation and presented by the HLAA*11:01/beta2microglobulin (beta2m) complex, is a pivotal antigenic target in antitumor immunity. This complex plays a crucial role by activating specific cytotoxic T lymphocytes (CTLs), enabling the immune system to recognize and eliminate tumor cells harboring the KRAS G12R mutation. - Proteine/Peptide

Product Properties

• Molecular Weight: 36.0 kDa and 11.7 kDa
• Tag: C-10*His & C-Avi
• NCBI: 5
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: HLA-A*1101 & B2M & KRASG12R (VVVGARGVGK)

Images

Immobilized Biotinylated Human HLA-A*11:01&B2M&KRASG12R (VVVGARGVGK) Complex Protein (Cat. No. HLR-H82E2) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Anti-HLA class I Antibody, Human IgG1 (W6/32) with a linear range of 0.2-3 ng/mL (QC tested).

Immobilized Anti-HLA class I Antibody, Human IgG1 (W6/32) at 1 µg/mL (100 µL/well) can bind Biotinylated Human HLA-A*11:01&B2M&KRASG12R (VVVGARGVGK) Complex Protein (Cat. No. HLR-H82E2) with a linear range of 0.1-4 ng/mL (Routinely tested).

Biotinylated Human HLA-A*11:01&B2M&KRASG12R (VVVGARGVGK) Complex Protein on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.