Biotinylated Human HLA-A*03:01&B2M&Survivin Mut (RISTFKNWPK) Complex Protein (Monomer, MALS verified)

Product Overview

• Article Name: Biotinylated Human HLA-A*03:01&B2M&Survivin Mut (RISTFKNWPK) Complex Protein (Monomer, MALS verified)
• Biozol Catalog Number: ABS-HLT-H82E3-200UG
• Supplier Catalog Number: HLT-H82E3-200ug
• Alternative Catalog Number: ABS-HLT-H82E3-200UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

The peptide RISTFKNWPK, derived from a survivin mutant, is presented by the HLAA*03:01/beta2m complex and serves as a promising neoantigen target. Its presentation enables cytotoxic T lymphocytes (CTLs) to recognize and attack tumor cells overexpressing this mutated survivin variant, which is often associated with cancer cell survival and therapy resistance, offering a potential avenue for specific immunotherapy. - Proteine/Peptide

Product Properties

• Molecular Weight: 36.1 kDa and 11.7 kDa
• Tag: C-10*His & C-Avi
• NCBI: 04439
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: HLA-A*0301 & B2M & Survivin Mut (RISTFKNWPK)

Images

Immobilized Anti-HLA class I Antibody, Human IgG1 (W6/32) at 1 µg/mL (100 µL/well) can bind Biotinylated Human HLA-A*03:01&B2M&Survivin Mut (RISTFKNWPK) Complex Protein (Cat. No. HLT-H82E3) with a linear range of 0.1-4 ng/mL (QC tested).

Immobilized Biotinylated Human HLA-A*03:01&B2M&Survivin Mut (RISTFKNWPK) Complex Protein (Cat. No. HLT-H82E3) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Anti-HLA class I Antibody, Human IgG1 (W6/32) with a linear range of 0.2-3 ng/mL (Routinely tested).

Biotinylated Human HLA-A*03:01&B2M&Survivin Mut (RISTFKNWPK) Complex Protein on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.