APC-Labeled Human HLA-A*02:01&B2M&hTERT (ILAKFLHWL) Tetramer Protein

Product Overview

• Article Name: APC-Labeled Human HLA-A*02:01&B2M&hTERT (ILAKFLHWL) Tetramer Protein
• Biozol Catalog Number: ABS-HLT-HA2H7-200UG
• Supplier Catalog Number: HLT-HA2H7-200ug
• Alternative Catalog Number: ABS-HLT-HA2H7-200UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: APC

Product Description

hTERT (human Telomerase Reverse Transcriptase), the catalytic subunit of telomerase, maintains telomere length to drive tumor cells unlimited proliferation. It is highly expressed in ~8590% of cancers but silenced in most normal somatic cells. The peptide ILAKFLHWL (from hTERT residues 540548) acts as a tumorspecific antigen. It binds to MHC class I molecule HLAA0201 to form a surface complex on tumors, activating cytotoxic T lymphocytes (CTLs). The Human HLAA*0201 hTERT (ILAKFLHWL) complex protein is a complex of HLAA*0201 of the MHC Class I, B2M, and ILAKFLHWL peptide of the hTERT. - Proteine/Peptide

Product Properties

• Molecular Weight: 36.3 kDa and 11.7 kDa
• Tag: C-10*His
• NCBI: 59606
• Buffer: PBS, 1% BSA, pH7.4
• Form: Powder
• Target: HLA-A*0201 & B2M & hTERT (ILAKFLHWL)

Images

HLT-HA2H7-200ug