Biotinylated Human HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Complex Protein (Monomer, MALS verified)

Product Overview

• Article Name: Biotinylated Human HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Complex Protein (Monomer, MALS verified)
• Biozol Catalog Number: ABS-HLW-H82E5-200UG
• Supplier Catalog Number: HLW-H82E5-200ug
• Alternative Catalog Number: ABS-HLW-H82E5-200UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

Wilms tumor gene 1 (WT1),is an attractive target antigen for leukemia and solid cancer. WT1specific adoptive immunotherapy has developed for tumor treatment in recent years. WT1 has been proved wildly expressed in breast, colon and ovarian cancer. It participates in cell growth, differentiation and apoptosis regulation. The WT1127134 (RMFPNAPYL) was shown to be recognized by HLAA*0201 tumorinfiltrating lymphocytes from melanoma patients, and therefore it is widely been studied in TCRT studies. The Human HLAA*0201 WT1 (RMFPNAPYL) complex Protein is a complex of HLAA*0201 of the MHC Class I, B2M and RMFPNAPYL peptide of the WT1. - Proteine/Peptide

Product Properties

• Molecular Weight: 36.0 kDa and 13.9 kDa
• Tag: C-10*His & C-Avi
• NCBI: 59606
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: HLA-A*02:01 & B2M & WT-1 (RMFPNAPYL)

Images

Immobilized Biotinylated Human HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Complex Protein (Cat. No. HLW-H82E5) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Anti-HLA class I Antibody, Human IgG1 (W6/32) with a linear range of 0.0005-0.49 ng/mL ng/mL (QC tested).

Immobilized Biotinylated Human HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Complex Protein (Cat. No. HLW-H82E5) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Anti-B2M Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (Routinely tested).

Biotinylated Human HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Complex Protein on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.