Biotinylated Human HVEM / TNFRSF14 Protein, Fc,Avitag(TM) (MALS verified)

Product Overview

• Article Name: Biotinylated Human HVEM / TNFRSF14 Protein, Fc,Avitag(TM) (MALS verified)
• Biozol Catalog Number: ABS-HVM-H82F6-200UG
• Supplier Catalog Number: HVM-H82F6-200ug
• Alternative Catalog Number: ABS-HVM-H82F6-200UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

Herpesvirus entry mediator (HVEM) is also known as TNFRSF14, TR2 (TNF receptorlike molecule) and ATAR (another TRAF associated receptor), is a type I membrane protein belonging to the TNF/NGF receptor superfamily. HVEM expression has been detected in peripheral blood T cells, B cells, monocytes and in various tissues enriched in lymphoid cells. The extracellular domain of HVEM has been shown to interact directly with the herpes simplex virus envelope glycoprotein D (gD). Two TNF superfamily ligands, including the secreted TNFbeta (lymphotoxin alpha) and the membrane protein LIGHT (lymphotoxins, exhibits inducible expression, and competes with HSV glycoprotein D for HVEM, a receptor expressed by T lymphocytes), have been shown to be the cellular ligands for HVEM. Besides HVEM, LIGHT can also interact with LTbetaR, the receptor for lymphotoxin alphabeta heterotrimer. The role of the HVEM LIGHT /LTbeta receptor ligand pair in immune function and herpesvirus pathobiology remains to be elucidated. - Proteine/Peptide

Product Properties

• Molecular Weight: 45.5 kDa
• Tag: C-Fc & C-Avi
• NCBI: 92956
• Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
• Purity: 95%
• Form: Powder
• Target: HVEM

Images

Immobilized Human LIGHT, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. LIT-H5256) at 2 µg/mL (100 µL/well) can bind Biotinylated Human HVEM, Fc,Avitag (Cat. No. HVM-H82F6) with a linear range of 0.6-39 ng/mL (QC tested).

Immobilized Biotinylated Human HVEM, Fc,Avitag (Cat. No. HVM-H82F6) at 5 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Human CD160 Protein, His Tag with a linear range of 1-78 ng/mL (Routinely tested).

Biotinylated Human HVEM, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.