Human IDO1 Protein, His Tag (active enzyme, MALS verified), Unconjugated, E. coli 1 mg

Product Overview

• Article Name: Human IDO1 Protein, His Tag (active enzyme, MALS verified), Unconjugated, E. coli 1 mg
• Biozol Catalog Number: ABS-ID1-H5143-1MG
• Supplier Catalog Number: ID1-H5143-1mg
• Alternative Catalog Number: ABS-ID1-H5143-1MG
• Manufacturer: AcroBiosystems
• Host: E. coli
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

This gene encodes indoleamine 2,3dioxygenase (IDO) a heme enzyme that catalyzes the first and ratelimiting step in tryptophan catabolism to Nformylkynurenine. This enzyme acts on multiple tryptophan substrates including Dtryptophan, Ltryptophan, 5hydroxytryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates Tcell behavior by its pericellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011] - Proteine/Peptide

Product Properties

• Molecular Weight: 47.2 kDa
• Tag: N-10*His
• NCBI: 14902
• Buffer: 20 mM Tris, 300 mM NaCl, pH7.5
• Purity: 90%
• Form: Liquid
• Target: IDO1

Images

Human IDO1 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.