Human IFN-alpha/beta R2 Protein, His Tag (MALS verified), Unconjugated

Product Overview

• Article Name: Human IFN-alpha/beta R2 Protein, His Tag (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-IF2-H5224-1MG
• Supplier Catalog Number: IF2-H5224-1mg
• Alternative Catalog Number: ABS-IF2-H5224-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Interferon alpha/beta receptor 2 (IFNAR2) is also known as IFNalpha binding protein, IFNalpha/beta receptor 2, Type I interferon receptor 2, IFNABR and IFNARB, which is a singlepass type I membrane protein and belongs to the type II cytokine receptor family. IFNAR2 can associate with IFNAR1 to form the type I interferon receptor. IFNAR2 is a receptor for interferons alpha and beta.IFNAR2 involves in IFNmediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 of IFNAR2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 of IFNAR2 is a potent inhibitor of type I IFN receptor activity.Genetic variations in IFNAR2 influence susceptibility to hepatitis B virus (HBV) infection. - Proteine/Peptide

Product Properties

• Molecular Weight: 25.8 kDa
• Tag: C-8*His
• NCBI: 48551
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: IFN-alpha/beta R2

Images

Human IFNAR2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

IF2-H5224-1mg

Immobilized Human IFNAR2, His Tag (Cat. No. IF2-H5224) at 5 µg/mL (100 µL/well) can bind Human IFN-alpha 2a (R46K) Protein, Fc Tag (Cat. No. IFA-H5253) with a linear range of 1-40 ng/mL (Routinely tested).

Immobilized Human IFNAR2, His Tag (Cat. No. IF2-H5224) at 5 µg/mL (100 µL/well) can bind Human IFN-beta Protein, Fc Tag (Cat. No. IFB-H5254) with a linear range of 0.03-2 ng/mL (Routinely tested).