Rat IFN-alpha/beta R2 Protein, His Tag, Unconjugated, Human
Biozol Catalog Number:
ABS-IFA-R52H1-1MG
Supplier Catalog Number:
IFA-R52H1-1mg
Alternative Catalog Number:
ABS-IFA-R52H1-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Rat
Conjugation:
Unconjugated
Interferon alpha/beta receptor 2 (IFR2) is also known as IFNalpha binding protein, IFNalpha/beta receptor 2, Type I interferon receptor 2, IFBR and IFRB, which is a singlepass type I membrane protein and belongs to the type II cytokine receptor family. IFR2 can associate with IFR1 to form the type I interferon receptor. IFR2 is a receptor for interferons alpha and beta.IFR2 involves in IFNmediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 of IFR2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 of IFR2 is a potent inhibitor of type I IFN receptor activity.Genetic variations in IFR2 influence susceptibility to hepatitis B virus (HBV) infection. - Proteine/Peptide
Rat IFN-alpha/beta R2 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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