Human IFN-gamma / IFNG Protein, Research Grade, Unconjugated
Biozol Catalog Number:
ABS-IFG-H5213-20UG
Supplier Catalog Number:
IFG-H5213-20ug
Alternative Catalog Number:
ABS-IFG-H5213-20UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Interferongamma (IFNgamma/IFNG) is a dimerized soluble cytokine that is the only member of the type II class of interferon. This interferon was originally called macrophageactivating factor, a term now used to describe a larger family of proteins to which IFNgamma belongs. IFNgamma has been used in a wide variety of clinical indications. Interferongamma (IFNgamma) is a central regulator of the immune response and signals via the Janus Activated Kinase (JAK)Signal Transducer and Activator of Transcription (STAT) pathway. Interferon gamma has broader roles in activation of innate and adaptive immune responses to viruses and tumors, in part through upregulating transcription of genes involved in cell cycle regulation, apoptosis, and antigen processing/presentation. Despite this, rodent and human trophoblast cells show dampened responses to IFNG that reflect the resistance of these cells to IFNGmediated activation of major histocompatibility complex (MHC) class II transplantation antigen expression. - Proteine/Peptide
Human IFN-gamma Protein, Research Grade on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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