Human IgG1 Fc (C103S, D239E, L241E) Protein, Tag Free (MALS verified), Unconjugated

Product Overview

• Article Name: Human IgG1 Fc (C103S, D239E, L241E) Protein, Tag Free (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-IG1-H52H1-200UG
• Supplier Catalog Number: IG1-H52H1-200ug
• Alternative Catalog Number: ABS-IG1-H52H1-200UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Crystallizable fragments composed of the carboxyterminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxyterminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential antiinflammatory drug for treatment of human autoimmune diseases. - Proteine/Peptide

Product Properties

• Molecular Weight: 26 kDa
• Tag: Native
• NCBI: 01857
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: IgG1 Fc

Images

Immobilized Human IgG1 Fc (C103S, D239E, L241E), Tag Free (Cat. No. IG1-H52H1) at 5 µg/mL (100 µL/well) can bind Biotinylated Human CD64, His,Avitag (Cat. No. FCA-H82E8) with a linear range of 0.3-2 ng/mL (QC tested).

Immobilized Human IgG1 Fc (C103S, D239E, L241E), Tag Free (Cat. No. IG1-H52H1) at 5 µg/mL (100 µL/well) can bind Biotinylated Human CD16a (V176) Protein, Avitag,His Tag (Cat. No. CDA-H82E9) with a linear range of 0.02-0.625 µg/mL (Routinely tested).

Human IgG1 Fc (C103S, D239E, L241E), Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.