Biotinylated Human IGSF8 Protein, Avitag(TM),His Tag (MALS verified)

Product Overview

• Article Name: Biotinylated Human IGSF8 Protein, Avitag(TM),His Tag (MALS verified)
• Biozol Catalog Number: ABS-IG8-H82Q3-25UG
• Supplier Catalog Number: IG8-H82Q3-25ug
• Alternative Catalog Number: ABS-IG8-H82Q3-25UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

IGSF8 (Immunoglobulin superfamily member 8) is a member the EWI subfamily of the immunoglobulin protein superfamily, also known as EWI2, KCT4, LIRD1, and PGRL. It interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. IGSF8 suppresses Tcell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin5 with CD9 and CD81 as key linkers. It may also play a role on integrindependent morphology and motility functions, and may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. Recent research indicates that IGSF8 is highly expressed on malignant cells with antigen presentation defects, and it interacts with NK receptors to suppress NK cell cytotoxicity. - Proteine/Peptide

Product Properties

• Molecular Weight: 62.1 kDa
• Tag: N-Avi & N-10*His
• NCBI: 969
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: IGSF8

Images

Biotinylated Human IGSF8 Protein, Avitag,His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.