Human IGF-II R Protein, His Tag (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-IGR-H53H3-1MG
Supplier Catalog Number:
IGR-H53H3-1mg
Alternative Catalog Number:
ABS-IGR-H53H3-1MG
Manufacturer:
AcroBiosystems
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
IGF2R, also known as the cationindependent mannose6phosphate receptor, is found ubiquitously in human tissues with a truncated soluble form of the receptor present in the circulation. Fulllength, 300kDa, IGF2R comprises a large Nterminal extracellular region of 15 homologous domains, a single membranespanning region and a small cytoplasmic tail. In addition to IGFII binding, major IGF2R functions include sorting newly synthesized lysosomal enzymes and endocytosis of extracellular lysosomal enzymes. To perform these disparate functions, the extracellular region contains binding sites for IGFII and phosphomannosyl residues - Proteine/Peptide
Immobilized Biotinylated Human IGF-II, Avitag,Fc Tag (Cat. No. IG2-H82F9) at 5 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Human IGF-II R Protein, His Tag (Cat. No. IGR-H53H3) with a linear range of 2-78 ng/mL (QC tested).
Immobilized Human IGF-II R Protein, His Tag (Cat. No. IGR-H53H3) at 5 µg/mL (100 µL/well) can bind Human IGF-II, Fc Tag (Cat. No. IG2-H4260) with a linear range of 2-20 ng/mL (Routinely tested).
Human IGF-II R Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
IGR-H53H3-1mg
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