Biotinylated Cynomolgus IL-11 Protein, His,Avitag(TM), Human

Product Overview

• Article Name: Biotinylated Cynomolgus IL-11 Protein, His,Avitag(TM), Human
• Biozol Catalog Number: ABS-IL1-C82Q3-200UG
• Supplier Catalog Number: IL1-C82Q3-200ug
• Alternative Catalog Number: ABS-IL1-C82Q3-200UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Monkey
• Conjugation: Biotin

Product Description

Interleukin11 (IL11) is a pleiotropic cytokine that stimulates megakaryocytopoiesis, resulting in increased production of platelets, as well as activating osteoclasts, inhibiting epithelial cell proliferation and apoptosis, and inhibiting macrophage mediator production. These functions may be particularly important in mediating the hematopoietic, osseous and mucosal protective effects of IL11. The cytokine also possesses antiinflammatory activity, and has been proposed as a therapeutic agent in the treatment of chronic inflammatory diseases, such as Crohns disease and rheumatoid arthritis. Although IL11 was initially believed to be restricted to mammals, subsequent studies demonstrated it to be expressed in fish. Despite close similarity in gene structure and conservation of key amino acids between fish and mammalian IL11, they share relatively low overall amino acid identity and may not necessarily be functionally analogous. - Proteine/Peptide

Product Properties

• Molecular Weight: 23 kDa
• Tag: N-10*His & N-Avi
• NCBI: 20808
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: IL-11

Images

Immobilized Biotinylated Cynomolgus IL-11 Protein, His,Avitag (Cat. No. IL1-C82Q3) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Human IL-11 R alpha, Fc Tag (Cat. No. ILR-H5256) with a linear range of 0.6-10 ng/mL (QC tested).

Immobilized Biotinylated Cynomolgus IL-11 Protein, His,Avitag (Cat. No. IL1-C82Q3) at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 µg/well) plate can bind Anti-IL11,Human,Human IgG1 (K214R, D356E, L358M) with a linear range of 0.6-10 ng/mL (Routinely tested).

Biotinylated Cynomolgus IL-11 Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.