Human IL-31 Protein, His Tag, low Endotoxin (MALS verified), Unconjugated

Product Overview

• Article Name: Human IL-31 Protein, His Tag, low Endotoxin (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-IL1-H5247-100UG
• Supplier Catalog Number: IL1-H5247-100ug
• Alternative Catalog Number: ABS-IL1-H5247-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

IL31 is an inflammatory cytokine that helps trigger cellmediated immunity against pathogens. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. May function in skin immunity. IL31 is produced by a variety of cells, namely type 2 helper (TH2) Tcells. IL31 sends signals through a receptor complex made of IL31RA and oncostatin M receptor beta (OSMRbeta) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways. - Proteine/Peptide

Product Properties

• Molecular Weight: 17.7 kDa
• Tag: N-10*His
• NCBI: 6
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: IL-31

Images

Immobilized Human IL-31, His Tag (Cat. No. IL1-H5247) at 1 µg/mL (100 µL/well) can bind Human IL-31 RA, Fc Tag (Cat. No. ILA-H5256) with a linear range of 0.02-0.625 µg/mL (QC tested).

Human IL-31, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

IL1-H5247-100ug