Biotinylated Human IL-12B&IL-12A Heterodimer Protein, His,Avitag(TM)&Flag Tag (MALS verified)

Product Overview

• Article Name: Biotinylated Human IL-12B&IL-12A Heterodimer Protein, His,Avitag(TM)&Flag Tag (MALS verified)
• Biozol Catalog Number: ABS-IL2-H8210-25UG
• Supplier Catalog Number: IL2-H8210-25ug
• Alternative Catalog Number: ABS-IL2-H8210-25UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

Interleukin 12 (IL12) is also known as p70, and is an interleukin that is naturally produced by dendritic cells, macrophages and human Blymphoblastoid cells (NC37) in response to antigenic stimulation.IL12 is a heterodimeric cytokine, containing IL12A (p35) and IL12B (p40). IL12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cellstimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of IFNgamma and TNFalpha from T cells and NK cells, and reduces IL4 mediated suppression of IFNgamma. IL12 plays an important role in the activities of natural killer cells and T lymphocytes. IL12 also has antiangiogenic activity, which means it can block the formation of new blood vessels. - Proteine/Peptide

Product Properties

• Molecular Weight: 38.3 kDa & 23.8 kDa
• Tag: C-10*His & C-Avi | C-Flag
• NCBI: 29460
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: IL-12B & IL-12A

Images

Immobilized Human IL-12 R beta 1, Fc Tag (Cat. No. ILB-H5255) at 5 µg/mL (100 µL/well) can bind Biotinylated Human IL-12B&IL-12A Heterodimer, His,Avitag&Flag Tag (Cat. No. IL2-H8210) with a linear range of 0.2-2.5 µg/mL (QC tested).

Immobilized Biotinylated Human IL-12B&IL-12A Heterodimer Protein, His,Avitag&Flag Tag (Cat. No. IL2-H8210) at 1 µg/mL (100 µL/well)on streptavidin precoated (0.5 µg/well) plate. can bind Monoclonal Anti-Human IL23A&IL12B P40 domain Antibody, Human IgG1 with a linear range of 0.2-1 ng/mL (Routinely tested).

Biotinylated Human IL-12B&IL-12A Heterodimer, His,Avitag&Flag Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.