Canine IL-13 Protein, His Tag (MALS verified), Unconjugated, Human
Biozol Catalog Number:
ABS-IL3-C52H4-500UG
Supplier Catalog Number:
IL3-C52H4-500ug
Alternative Catalog Number:
ABS-IL3-C52H4-500UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Canine
Conjugation:
Unconjugated
Interleukin 13 (IL13) is also known as ALRH, BHR1and P600, is a singlechain glycosylated polypeptide, and is a cytokine critical in regulating inflammatory and immune responses. IL13 is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL13 induces its effects through a multisubunit receptor that includes the alpha chain of the IL4 receptor (IL4Ralpha) and at least one of two known IL13specific binding chains. The functions of IL13 overlap considerably with those of IL4, especially with regard to changes induced on hematopoietic cells, but these effects are probably less important given the more potent role of IL4. IL13 induces matrix metalloproteinases (MMPs) as part of a mechanism that protects against excessive allergic inflammation that predisposes to asphyxiation. IL13 induces many features of allergic lung disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, which all contribute to airway obstruction. - Proteine/Peptide
Immobilized Canine IL-13, His Tag (Cat. No. IL3-C52H4) at 5 µg/mL (100 µL/well) can bind Human IL-13 R alpha 2 Protein, Fc Tag (Cat. No. IL2-H5256) with a linear range of 0.6-20 ng/mL (QC tested).
Immobilized Canine IL-13, His Tag (Cat. No. IL3-C52H4) at 5 µg/mL (100 µL/well) can bind Biotinylated Human IL-13 R alpha 1, Fc,Avitag (Cat. No. IL1-H82F6) with a linear range of 0.01-0.313 µg/mL (Routinely tested).
Canine IL-13, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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