Cynomolgus IL-4 Protein, His Tag (MALS verified), Unconjugated, Human
Biozol Catalog Number:
ABS-IL4-C52H9-1MG
Supplier Catalog Number:
IL4-C52H9-1mg
Alternative Catalog Number:
ABS-IL4-C52H9-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Monkey
Conjugation:
Unconjugated
Interleukin4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells to Th2 cells). In the presence of IL4 and IL13, cytokines that are produced in a Th2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Recently, researcher found that the cytokine IL4 plays a key role in development of innate CD8+ T cells in the thymus of several genedeficient mouse strains, including Itk, KLF2, CBP and Id3, without previous exposure to antigen. - Proteine/Peptide
