Human IL-2 R alpha / CD25 Protein, Fc Tag, low Endotoxin (MALS verified), Unconjugated

Product Overview

• Article Name: Human IL-2 R alpha / CD25 Protein, Fc Tag, low Endotoxin (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-ILA-H5251-1MG
• Supplier Catalog Number: ILA-H5251-1mg
• Alternative Catalog Number: ABS-ILA-H5251-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Interleukin2 receptor subunit alpha (IL2RA) is also known as IL2R subunit alpha, IL2RA, IL2RA, TAC antigen, p55, CD antigen CD25, is a type I transmembrane glycoprotein. IL2RA is expressed on activated T cells and regulatory T cells, and is capable of binding IL2 with low affinity by itself. However, a ligandinduced high affinity heterotrimeric receptor complex is produced when IL2RA is associated noncovelently with the IL2 receptor beta and gamma chain, and subsequently initiates the intacellular signal pathways such as MAPK or JAK/STAT. On dendritic cells (DC), CD25 has been previously regarded as an activation marker, while both murine and human DC can express CD25, they do not express the betachain of the IL2 receptor, which is indispensable for the execution of IL2 signaling. - Proteine/Peptide

Product Properties

• Molecular Weight: 48.4 kDa
• Tag: C-Fc
• NCBI: 000408
• Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Purity: 95%
• Form: Powder
• Target: IL-2 R alpha

Images

Immobilized Human IL-2 R alpha Protein, Fc Tag (Cat. No. ILA-H5251) at 2 µg/mL (100 µL/well) can bind Human IL-2, Tag Free with a linear range of 0.4-3 ng/mL (QC tested).

Human IL-2 R alpha Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

ILA-H5251-1mg