Human IL-17 RA / CD217 Protein, Fc Tag (MALS verified), Unconjugated

Product Overview

• Article Name: Human IL-17 RA / CD217 Protein, Fc Tag (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-ILA-H525F-1MG
• Supplier Catalog Number: ILA-H525f-1mg
• Alternative Catalog Number: ABS-ILA-H525F-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Interleukin 17 receptor A (IL17RA) is also known as cluster of differentiation w217 (CDw217), is a proinflammatory cytokine secreted by activated Tlymphocytes, belong to ubiquitous type I membrane glycoprotein, and binds with low affinity to interleukin 17A (IL17A). IL 17R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested . IL 17RA associates with IL 17RC to form a signaling receptor complex for IL 17 and IL 17F . Ligand and IL 17RA ligation promotes T cell activation and the production of IL 6, GCSF, SCF, and multiple proinflammatory chemokines. Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5). - Proteine/Peptide

Product Properties

• Molecular Weight: 59.9 kDa
• Tag: C-Fc
• NCBI: 96
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: IL-17 RA

Images

Immobilized Human IL-17F, His Tag (Cat. No. ILF-H5244) at 2 µg/mL (100 µL/well) can bind Human IL-17 RA Protein, Fc Tag (Cat. No. ILA-H525f) with a linear range of 4-63 ng/mL (QC tested).

Immobilized Human IL-17 RA Protein, Fc Tag (Cat. No. ILA-H525f) at 2 µg/mL (100 µL/well) can bind Biotinylated Human IL17A, His,Avitag (Cat. No. ILA-H82Q1) with a linear range of 0.1-2 ng/mL (Routinely tested).

Human IL-17 RA Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.