Human IL-2 R alpha / CD25 Protein, His Tag (MALS verified), Unconjugated

Product Overview

• Article Name: Human IL-2 R alpha / CD25 Protein, His Tag (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-ILA-H52H9-100UG
• Supplier Catalog Number: ILA-H52H9-100ug
• Alternative Catalog Number: ABS-ILA-H52H9-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Interleukin2 receptor subunit alpha (IL2RA) is also known as IL2R subunit alpha, IL2RA, IL2RA, TAC antigen, p55, CD antigen CD25, is a type I transmembrane glycoprotein. IL2RA is expressed on activated T cells and regulatory T cells, and is capable of binding IL2 with low affinity by itself. However, a ligandinduced high affinity heterotrimeric receptor complex is produced when IL2RA is associated noncovelently with the IL2 receptor beta and gamma chain, and subsequently initiates the intacellular signal pathways such as MAPK or JAK/STAT. On dendritic cells (DC), CD25 has been previously regarded as an activation marker, while both murine and human DC can express CD25, they do not express the betachain of the IL2 receptor, which is indispensable for the execution of IL2 signaling. - Proteine/Peptide

Product Properties

• Molecular Weight: 23.6 kDa
• Tag: C-10*His
• NCBI: 000408
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Powder
• Target: IL-2 R alpha

Images

Immobilized Biotinylated Human IL-2, Fc,Avitag (Cat. No. IL2-H82F3) at 1 µg/mL (100 µL/well) on streptavidin precoated (0.2 µg/well) plate, can bind Human IL-2 R alpha, His Tag (Cat. No. ILA-H52H9) with a linear range of 1-39 ng/mL (QC tested).

Human IL-2 R alpha, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

ILA-H52H9-100ug