Biotinylated Mouse IL-2 R alpha / CD25 Protein, His,Avitag(TM) (MALS verified), Human
Biozol Catalog Number:
ABS-ILA-M82E9-200UG
Supplier Catalog Number:
ILA-M82E9-200ug
Alternative Catalog Number:
ABS-ILA-M82E9-200UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Mouse
Conjugation:
Biotin
Interleukin2 receptor subunit alpha (IL2RA) is also known as IL2R subunit alpha, IL2RA, IL2RA, TAC antigen, p55, CD antigen CD25, is a type I transmembrane glycoprotein. IL2RA is expressed on activated T cells and regulatory T cells, and is capable of binding IL2 with low affinity by itself. However, a ligandinduced high affinity heterotrimeric receptor complex is produced when IL2RA is associated noncovelently with the IL2 receptor beta and gamma chain, and subsequently initiates the intacellular signal pathways such as MAPK or JAK/STAT. On dendritic cells (DC), CD25 has been previously regarded as an activation marker, while both murine and human DC can express CD25, they do not express the betachain of the IL2 receptor, which is indispensable for the execution of IL2 signaling. - Proteine/Peptide
Immobilized Human IL-2 Protein, Fc Tag (Cat. No. IL2-H5269) at 5 µg/mL (100 µL/well) can bind Biotinylated Mouse IL-2 R alpha Protein, His,Avitag (Cat. No. ILA-M82E9) with a linear range of 0.6-10 ng/mL (QC tested).
Immobilized Mouse IL-2, His Tag (Cat. No. IL2-M52H3) at 5 µg/mL (100 µL/well) can bind Biotinylated Mouse IL-2 R alpha Protein, His,Avitag (Cat. No. ILA-M82E9) with a linear range of 0.005-0.625 µg/mL (Routinely tested).
Biotinylated Mouse IL-2 R alpha Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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