Cynomolgus IL-23 alpha&Mouse IL-12 beta Heterodimer Protein, His Tag&Tag Free (MALS verified), Unconjugated, Human

Product Overview

• Article Name: Cynomolgus IL-23 alpha&Mouse IL-12 beta Heterodimer Protein, His Tag&Tag Free (MALS verified), Unconjugated, Human
• Biozol Catalog Number: ABS-ILB-CM52W8-50UG
• Supplier Catalog Number: ILB-CM52W8-50ug
• Alternative Catalog Number: ABS-ILB-CM52W8-50UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Monkey, Mouse
• Conjugation: Unconjugated

Product Description

Interleukin23 subunit alpha (IL23 alpha) can associates with IL12B to form the IL23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL23 may constitute with IL17 an acute response to infection in peripheral tissues. IL23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the JakStat signaling cascade, stimulates memory rather than naive Tcells and promotes production of proinflammatory cytokines. IL23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. - Proteine/Peptide

Product Properties

• Molecular Weight: 20.3 kDa (IL23A) & 35.8 kDa (IL12B)
• Tag: N-10*His | Native
• NCBI: 0
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: IL23A & IL12B

Images

ILB-CM52W8-50ug

Immobilized Biotinylated Human IL-23 R, Fc,Avitag (Cat. No. ILR-H82F3) at 1 µg/mL (100 µL/well) on Streptavidin precoated (0.5 µg/well) plate can bind Cynomolgus IL-23A & Mouse IL-12B Heterodimer Protein, His Tag&Tag Free (Cat. No. ILB-CM52W8) with a linear range of 0.03-0.25 µg/mL (QC tested).

Cynomolgus IL-23A&Mouse IL-12B Heterodimer Protein, His Tag&Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.