Human IL-23 alpha&Rat IL-12 beta Heterodimer Protein, His Tag&Tag Free, Ultra Low Endotoxin (MALS verified), Unconjugated
Biozol Catalog Number:
ABS-ILB-HR52W4-1MG
Supplier Catalog Number:
ILB-HR52W4-1mg
Alternative Catalog Number:
ABS-ILB-HR52W4-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human, Rat
Conjugation:
Unconjugated
Interleukin23 subunit alpha (IL23 alpha) can associates with IL12B to form the IL23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL23 may constitute with IL17 an acute response to infection in peripheral tissues. IL23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the JakStat signaling cascade, stimulates memory rather than naive Tcells and promotes production of proinflammatory cytokines. IL23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. - Proteine/Peptide
Immobilized Human IL-23 R, Fc Tag (Cat. No. ILR-H5254) at 5 µg/mL (100 µL/well) can bind Human IL-23A&Rat IL-12B Heterodimer Protein, His Tag&Tag Free (Cat. No. ILB-HR52W4) with a linear range of 0.02-0.625 µg/mL (QC tested).
Immobilized Human IL-23A&Rat IL-12B Heterodimer Protein, His Tag&Tag Free (Cat. No. ILB-HR52W4) at 5 µg/mL (100 µL/well) can bind HumanIL-12Rbeta1,FcTag with a linear range of 0.1-16 ng/mL (QC tested).
Human IL-23A&Rat IL-12B Heterodimer Protein, His Tag&Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
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