Human IL-17F (H161R) Protein, His Tag, Unconjugated

Catalog Number: ABS-ILF-H4240-1MG
Article Name: Human IL-17F (H161R) Protein, His Tag, Unconjugated
Biozol Catalog Number: ABS-ILF-H4240-1MG
Supplier Catalog Number: ILF-H4240-1mg
Alternative Catalog Number: ABS-ILF-H4240-1MG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Unconjugated
Interleukin17F (IL17F) is also known as Interleukin24 (IL24), Cytokine ML1, is a secreted disulfidelinked homodimer which belongs to the IL17 family. There are at least six members of the IL17 family in humans and in mice: IL17A, IL17B, IL17C, IL17D, IL17E (also called IL25) and IL17F (also called IL24). IL17 represents a family of structurally related cytokines that share a highly conserved Cterminal region but differ from one another in their Nterminal regions and in their distinct biological roles. IL17F / IL24 is expressed in activated, but not resting, CD4+ Tcells and activated monocytes. IL17F / Interleukin24 stimulates the production of other cytokines such as IL6, IL8 and granulocyte colonystimulating factor, and can regulate cartilage matrix turnover. IL17F / IL24 stimulates PBMC and Tcell proliferation and Inhibits angiogenesis. Defects in IL17F are the cause of familial candidiasis type 6 (CANDF6). - Proteine/Peptide
Molecular Weight: 16.8 kDa
Tag: N-6*His
NCBI: 96
Buffer: PBS, pH7.4
Purity: 95%
Form: Powder
Target: IL-17F
ILF-H4240-1mg
Immobilized Human IL-17F (H161R), His Tag (Cat. No. ILF-H4240) at 10 µg/mL (100 µL/well) can bind Biotinylated Human IL-17 RA, Fc,Avitag (Cat. No. ILA-H82F1) with a linear range of 0.02-0.313 µg/mL (QC tested).
Immobilized Human IL-17F (H161R), His Tag (Cat. No. ILF-H4240) at 10 µg/mL (100 µL/well) can bind Human IL-17 RA, Fc Tag with a linear range of 0.078-1.25 µg/mL (Routinely tested).
Human IL-17F (H161R), His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.