Human IL-18BP Protein, Fc Tag (MALS verified), Unconjugated

Catalog Number: ABS-ILP-H5253-1MG
Article Name: Human IL-18BP Protein, Fc Tag (MALS verified), Unconjugated
Biozol Catalog Number: ABS-ILP-H5253-1MG
Supplier Catalog Number: ILP-H5253-1mg
Alternative Catalog Number: ABS-ILP-H5253-1MG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Unconjugated
Interleukin18binding protein (IL18BP) is also known as Tadekinigalfa, IL18BPa, which functions as an IL18 inhibitor. IL18BP is a secreted protein which contains one Iglike C2type (immunoglobulinlike) domain. IL18BP does not have a transmembrane domain and hence is not anchored to the cell membrane. IL18BP is strongly expressed in heart, lung, placenta and spleen. Isoform A of IL18BP binds to IL18 and inhibits its activity. IL18BP also functions as an inhibitor of the early TH1 cytokine response. IL18BP suppresses the production of IFNgamma resulting in reduced Thelper type 1 immune responses. - Proteine/Peptide
Molecular Weight: 44.3 kDa
Tag: C-Fc
NCBI: 001138529
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
Purity: 95%
Form: Powder
Target: IL-18BP
Immobilized Human IL-18 Protein, premium grade (Cat. No. IL8-H5114) at 5 µg/mL (100 µL/well) can bind Human IL-18BP, Fc Tag (Cat. No. ILP-H5253) with a linear range of 0.6-20 ng/mL (QC tested).
Human IL-18BP, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
ILP-H5253-1mg