Biotinylated Cynomolgus IL-23 R Protein, His,Avitag(TM) (MALS & SPR verified), Human
Biozol Catalog Number:
ABS-ILR-C82E4-200UG
Supplier Catalog Number:
ILR-C82E4-200ug
Alternative Catalog Number:
ABS-ILR-C82E4-200UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Monkey
Conjugation:
Biotin
Interleukin 23 receptor (IL23R) is a type I cytokine receptor, and IL23R pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. Also, IL23R associates constitutively with Janus kinase 2 (JAK2), and binds to transcription activator STAT3 in a liganddependent manner. Furthermore, IL23R mediates Tcells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the JakStat signaling cascade. As for IL23, it may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. - Proteine/Peptide
Biotinylated Cynomolgus IL-23 R Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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