Human IL-23 R Protein, Fc Tag (MALS verified), Unconjugated

Product Overview

• Article Name: Human IL-23 R Protein, Fc Tag (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-ILR-H5254-100UG
• Supplier Catalog Number: ILR-H5254-100ug
• Alternative Catalog Number: ABS-ILR-H5254-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Interleukin 23 receptor (IL23R) is a type I cytokine receptor, and IL23R pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. Also, IL23R associates constitutively with Janus kinase 2 (JAK2), and binds to transcription activator STAT3 in a liganddependent manner. Furthermore, IL23R mediates Tcells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the JakStat signaling cascade. As for IL23, it may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. - Proteine/Peptide

Product Properties

• Molecular Weight: 64.5 kDa
• Tag: C-Fc
• NCBI: 5
• Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Purity: 95%
• Form: Powder
• Target: IL-23 R

Images

Immobilized Biotinylated Human IL-23A&IL-12B Heterodimer Protein, His,Avitag&Tag Free (Cat. No. ILB-H82W6) at 2 µg/mL (100 µL/well)on streptavidin (Cat. No. STN-N5116) precoated (0.2 µg/well) plate can bind Human IL-23 R, Fc Tag (Cat. No. ILR-H5254) with a linear range of 0.2-2 ng/mL (QC tested).

Human IL-23 R, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

ILR-H5254-100ug