Human IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag, Unconjugated

Catalog Number: ABS-ILR-H525X-1MG
Article Name: Human IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag, Unconjugated
Biozol Catalog Number: ABS-ILR-H525X-1MG
Supplier Catalog Number: ILR-H525x-1mg
Alternative Catalog Number: ABS-ILR-H525X-1MG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Unconjugated
TSLP is a pleiotropic cytokine originally characterized as a lymphocyte growth factor. Thymic stromal lymphopoietin (TSLP) is overexpressed in the airways of severe asthmatics and is an upstream cytokine that orchestrates inflammatory responses in asthma. Human TSLP exerts its biological activities by binding to a highaffinity heteromeric receptor complex composed of TSLPR and IL 7 receptor and initiates signaling in cells coexpressing TSLPR and IL7R. - Proteine/Peptide
Molecular Weight: 51.7 kDa (IL-7 RA) & 50.3 kDa (TSLP R)
Tag: C-Fc | C-Fc
NCBI: 16871
Buffer: PBS, pH7.4
Purity: 95%
Form: Powder
Target: IL-7 R alpha & TSLP R
ILR-H525x-1mg
Immobilized Human IL-7 RA&TSLP R Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. ILR-H525x) at 5 µg/mL (100 µL/well) can bind Biotinylated Human TSLP, His,Avitag (Cat. No. TSP-H82Eb) with a linear range of 0.1-2 ng/mL (QC tested).
Serial dilutions of Monoclonal Anti-Human TSLP Antibody, Human IgG2 were added into Human IL-7 RA&TSLP R Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. ILR-H525x) : Biotinylated Human TSLP, His,Avitag (Cat. No. TSP-H82Eb) binding reactions. The half maximal inhibitory concentration (IC50) is 0.21312 µg/mL (Routinely tested).
Human IL-7 RA&TSLP R Heterodimer Protein, Fc Tag&Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.