Canine Insulin R / CD220 (28-956) Protein, His Tag, Unconjugated, Human

Product Overview

• Article Name: Canine Insulin R / CD220 (28-956) Protein, His Tag, Unconjugated, Human
• Biozol Catalog Number: ABS-INR-D52H3-100UG
• Supplier Catalog Number: INR-D52H3-100ug
• Alternative Catalog Number: ABS-INR-D52H3-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Canine
• Conjugation: Unconjugated

Product Description

Insulin receptor (INSR) is also known as CD antigen CD220, which can be cleaved into the following 2 chains: Insulin receptor subunit alpha and Insulin receptor subunit beta. INSR is a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains carry the insulinbinding regions, while the beta chains carry the kinase domain. Forms a hybrid receptor with IGF1R, the hybrid is a tetramer consisting of 1 alpha chain and 1 beta chain of INSR and 1 alpha chain and 1 beta chain of IGF1R. In addition to binding insulin, the insulin receptor can bind insulinlike growth factors (IGFI and IGFII). Isoform Short of INSR has a higher affinity for IGFII binding. When present in a hybrid receptor with IGF1R, INSR binds IGF1. - Proteine/Peptide

Product Properties

• Molecular Weight: 107.5 kDa
• Tag: C-10*His
• NCBI: 0
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: Insulin R

Images

Canine Insulin R (28-956) Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.