Human Insulin R / CD220 (28-944) Protein, His Tag (MALS & SPR verified), Unconjugated

Product Overview

• Article Name: Human Insulin R / CD220 (28-944) Protein, His Tag (MALS & SPR verified), Unconjugated
• Biozol Catalog Number: ABS-INR-H52HA-100UG
• Supplier Catalog Number: INR-H52Ha-100ug
• Alternative Catalog Number: ABS-INR-H52HA-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Insulin receptor (INSR) is also known as CD antigen CD220, which can be cleaved into the following 2 chains: Insulin receptor subunit alpha and Insulin receptor subunit beta. INSR is a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains carry the insulinbinding regions, while the beta chains carry the kinase domain. Forms a hybrid receptor with IGF1R, the hybrid is a tetramer consisting of 1 alpha chain and 1 beta chain of INSR and 1 alpha chain and 1 beta chain of IGF1R. In addition to binding insulin, the insulin receptor can bind insulinlike growth factors (IGFI and IGFII). Isoform Short of INSR has a higher affinity for IGFII binding. When present in a hybrid receptor with IGF1R, INSR binds IGF1. - Proteine/Peptide

Product Properties

• Molecular Weight: 83.6 kDa and 22.8 kDa
• Tag: C-10*His
• NCBI: 06213
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: Insulin R

Images

Immobilized Human Insulin R (28-944), His Tag (Cat. No. INR-H52Ha) at 5 µg/mL (100 µL/well)can bind Human IGF-II, Fc Tag (Cat. No. IG2-H4260) with a linear range of 0.078-2.5 µg/mL (QC tested).

Immobilized Human Insulin R (28-944), His Tag (Cat. No. INR-H52Ha) at 5 µg/mL (100 µL/well)can bind InsulinBiotin Conjugate with a linear range of 0.02-0.313 µg/mL (Routinely tested).

Human Insulin R (28-944), His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

INR-H52Ha-100ug