Human IRAK4 Protein, GST Tag (active enzyme, HPLC verified), Unconjugated, Insect 1 mg
Biozol Catalog Number:
ABS-IR4-H5533-1MG
Supplier Catalog Number:
IR4-H5533-1mg
Alternative Catalog Number:
ABS-IR4-H5533-1MG
Manufacturer:
AcroBiosystems
Host:
Insect
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
This gene encodes a kinase that activates NFkappaB in both the Tolllike receptor (TLR) and Tcell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. - Proteine/Peptide