Biotinylated Human Integrin isoform alpha-7X2B beta 1 (ITGA7X2B&ITGB1) Heterodimer Protein, Avitag(TM)&His,Avitag(TM)

Product Overview

• Article Name: Biotinylated Human Integrin isoform alpha-7X2B beta 1 (ITGA7X2B&ITGB1) Heterodimer Protein, Avitag(TM)&His,Avitag(TM)
• Biozol Catalog Number: ABS-IT1-H82W5-200UG
• Supplier Catalog Number: IT1-H82W5-200ug
• Alternative Catalog Number: ABS-IT1-H82W5-200UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

Integrin alpha7/beta1 is the primary laminin receptor on skeletal myoblasts and adult myofibers, which is highly expressed in cardiac muscle, skeletal muscle and smooth muscle cells, and localizes to Zdisc and costamere structures. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha7X2B and isoform Alpha7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha7X1B is less active on laminin 1 (In vitro). ITGA7 has been shown to interact with Merosin, ITGB1, FHL2 and FHL3. - Proteine/Peptide

Product Properties

• Molecular Weight: 116.9 kDa (ITGA7X2B) & 86.7 kDa (ITGB1)
• Tag: Native | C-10*His & C-Avi
• NCBI: 13683
• Buffer: 50 mM Tris, 150 mM NaCl, pH7.5
• Purity: 90%
• Form: Powder
• Target: Integrin isoform alpha-7X2B beta 1

Images

Biotinylated Human ITGA7X2B&ITGB1 Heterodimer Protein, Avitag&His,Avitag on SDS-PAGE under non-reducing (NR) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.