Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, His Tag&Tag Free (MALS verified), Unconjugated

Product Overview

• Article Name: Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, His Tag&Tag Free (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-IT3-H52E3-100UG
• Supplier Catalog Number: IT3-H52E3-100ug
• Alternative Catalog Number: ABS-IT3-H52E3-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Integrin alphaV/beta3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrins alphaIIb/beta3 and alphaV/beta3 recognize the sequence RGD in a wide array of ligands. Also, Integrin alphaV/beta3 acts as a receptor for herpes virus 8/HHV8, coxsackievirus A9, Hantaan virus, cytomegalovirus/HHV5, human metapneumovirus, human parechovirus 1 and west nile virus. Furthermore, in case of HIV1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposis sarcoma lesions. - Proteine/Peptide

Product Properties

• Molecular Weight: 112.9 kDa (ITGAV) & 81.8 kDa (ITGB3)
• Tag: C-10*His | Native
• NCBI: 002201
• Buffer: 50 mM Tris, 150 mM NaCl, pH7.5
• Expression System: Phe 31 - Val 992 (ITGAV) & Gly 27 - Asp 718 (ITGB3)
• Purity: 95%
• Form: Powder
• Target: Integrin alpha V beta 3

Images

IT3-H52E3-100ug