Human Integrin alpha E beta 7 (ITGAE&ITGB7) Heterodimer Protein, His Tag&Tag Free (MALS verified), Unconjugated

Product Overview

• Article Name: Human Integrin alpha E beta 7 (ITGAE&ITGB7) Heterodimer Protein, His Tag&Tag Free (MALS verified), Unconjugated
• Biozol Catalog Number: ABS-IT7-H52W7-50UG
• Supplier Catalog Number: IT7-H52W7-50ug
• Alternative Catalog Number: ABS-IT7-H52W7-50UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Integrin alpha E beta 7 consist of two major subunits: Integrin alpha E (ITGAE) also known as CD103 (cluster of differentiation 103) and Integrin beta7 is an integrin protein that in humans is encoded by the ITGB7 gene. Integrin alpha E beta 7 (CD103) is expressed mainly by cells of the T lymphocyte lineage within mucosal tissues. This is a strikingly narrow pattern of expression compared with that of other integrins. Lymphocytes expressing alpha E beta 7 are abundant in the gut and comprise a major part of the total T cell complement of the body. The effectiveness of lung transplantation is marred by the relatively high incidence of rejection. The lung normally contains a large population of lymphocytes in contact with the airway epithelium, a proportion of which expresses the mucosal integrin, alpha(E)(CD103)beta(7). This integrin is not a homing receptor, but is thought to retain lymphocytes at the epithelial surface. - Proteine/Peptide

Product Properties

• Molecular Weight: 128.6 kDa (ITGAE) & 81.8 kDa (ITGB7)
• Tag: C-10*His | Native
• NCBI: 38570
• Buffer: 50 mM Tris, 150 mM NaCl, pH7.5
• Purity: 90%
• Form: Powder
• Target: Integrin alpha E beta 7

Images

Immobilized Human ITGAE&ITGB7 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT7-H52W7) at 5 µg/mL (100 µL/well) can bind Human E-Cadherin, Fc Tag, premium grade (Cat. No. ECD-H5250) with a linear range of 0.02-0.625 µg/mL (QC tested).

Immobilized Human ITGAE&ITGB7 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT7-H52W7) at 5 µg/mL (100 µL/well) can bind Human E-Cadherin (155-709) Protein, Fc Tag (Cat. No. ECD-H5256) with a linear range of 0.02-0.625 µg/mL (Routinely tested).

Human ITGAE&ITGB7 Heterodimer Protein, His Tag&Tag Free on SDS-PAGE under non-reducing (NR) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.