Human JAK1 Protein, His Tag, Unconjugated, Insect 50 ug

Product Overview

• Article Name: Human JAK1 Protein, His Tag, Unconjugated, Insect 50 ug
• Biozol Catalog Number: ABS-JA1-H5547-50UG
• Supplier Catalog Number: JA1-H5547-50ug
• Alternative Catalog Number: ABS-JA1-H5547-50UG
• Manufacturer: AcroBiosystems
• Host: Insect
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

JAK1 is a human tyrosine kinase protein essential for signaling for certain type I and type II cytokines. It interacts with the common gamma chain (gammac) of type I cytokine receptors, to elicit signals from the IL2 receptor family (e.g. IL2R, IL7R, IL9R and IL15R), the IL4 receptor family (e.g. IL4R and IL13R), the gp130 receptor family (e.g. IL6R, IL11R, LIFR, OSMR, cardiotrophin1 receptor (CT1R), ciliary neurotrophic factor receptor (CNTFR), neurotrophin1 receptor (NNT1R) and LeptinR). Jak1 plays a critical role in initiating responses to multiple major cytokine receptor families. Expression of JAK1 in cancer cells enables individual cells to contract, potentially allowing them to escape their tumor and metastasize to other parts of the body - Proteine/Peptide

Product Properties

• Molecular Weight: 35.7 kDa
• Tag: N-10*His
• NCBI: 23458
• Buffer: 50 mM Tris, 500 mM NaCl, pH8.0
• Purity: 95%
• Form: Liquid
• Target: JAK1

Images

Human JAK1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.