Cynomolgus Kallikrein 5 Protein, His Tag (active enzyme, HPLC verified), Unconjugated, Human

Product Overview

• Article Name: Cynomolgus Kallikrein 5 Protein, His Tag (active enzyme, HPLC verified), Unconjugated, Human
• Biozol Catalog Number: ABS-KA5-C52H3-100UG
• Supplier Catalog Number: KA5-C52H3-100ug
• Alternative Catalog Number: ABS-KA5-C52H3-100UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Monkey
• Conjugation: Unconjugated

Product Description

Kallikrein-related peptidase 5 (KLK5) is a secreted serine protease encoded by the KLK5 gene on chromosome 19q13.4. It is synthesized as an inactive zymogen and activated extracellularly, where it participates in proteolytic cascades with other kallikreins. KLK5 is highly expressed in the skin, particularly in the stratum corneum, where it regulates desquamation by cleaving corneodesmosomal proteins. Dysregulated KLK5 activity contributes to impaired barrier function and inflammatory skin disorders such as Netherton syndrome, atopic dermatitis, and rosacea. Beyond dermatology, KLK5 has been implicated in cancer biology, extracellular matrix remodeling, and as a potential biomarker and therapeutic target. - Proteine/Peptide

Product Properties

• Molecular Weight: 26.9 kDa
• Tag: C-10*His
• NCBI: 005590111
• Buffer: 50 mM Tris, 150 mM NaCl, pH7.5
• Purity: 95%
• Form: Powder
• Target: Kallikrein 5

Images

Cynomolgus Kallikrein 5 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.