Human KIR2DL4 / CD158d Protein, Fc Tag, Unconjugated

Product Overview

• Article Name: Human KIR2DL4 / CD158d Protein, Fc Tag, Unconjugated
• Biozol Catalog Number: ABS-KI4-H5255-1MG
• Supplier Catalog Number: KI4-H5255-1mg
• Alternative Catalog Number: ABS-KI4-H5255-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

Killer cell immunoglobulinlike receptor 2DL4(KIR2DL4), which belongs to the immunoglobulin superfamily, is an inhibitory receptor of NK cells. Soluble HLAG binds to KIR2DL4 in endosomes and activates the pathway of DNAPKcs (DNAdependent protein kinase, catalytic subunit)AKTNFkappaB signals. The stimulation of the ITIM of KIR2DL4 protein brings about the recruitment and activation of nonreceptor protein phosphatases Src homology 2 domaincontaining tyrosine phosphatase (SHP)1 and SHP2, and the following inhibition of CD16/FcgammaRIIIa signaling pathway in human NK cells. - Proteine/Peptide

Product Properties

• Molecular Weight: 50.5 kDa
• Tag: C-Fc
• NCBI: 99706
• Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
• Purity: 90%
• Form: Powder
• Target: KIR2DL4

Images

Human KIR2DL4, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.