Biotinylated Cynomolgus KLRG1 Protein, Avitag(TM),His Tag, Human

Product Overview

• Article Name: Biotinylated Cynomolgus KLRG1 Protein, Avitag(TM),His Tag, Human
• Biozol Catalog Number: ABS-KL1-C82Q4-200UG
• Supplier Catalog Number: KL1-C82Q4-200ug
• Alternative Catalog Number: ABS-KL1-C82Q4-200UG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Monkey
• Conjugation: Biotin

Product Description

The coinhibitory receptor killercell lectin like receptor G1 (KLRG1) is specifically expressed on NK cells and activated CD8+ Tcells and has been postulated to be a marker of senescence. KLRG1+ T cells are a major reason of chronic tissue damage in some autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. In tumors, tumor cells which express Ecadherin or Ncadherin bind to KLRG1 and inhibit the antitumor activity of T and NK cells. Thus, KLRG1 acts as an immunocheckpoint inhibitory receptor. - Proteine/Peptide

Product Properties

• Molecular Weight: 18.5 kDa
• Tag: N-Avi & N-10*His
• NCBI: 0
• Buffer: PBS, pH7.4
• Purity: 90%
• Form: Powder
• Target: KLRG1

Images

Biotinylated Cynomolgus KLRG1 Protein, Avitag,His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.