Human Kallikrein 8 / KLK-8 Protein, His Tag (active enzyme, MALS verified), Unconjugated
Biozol Catalog Number:
ABS-KL8-H52H3-100UG
Supplier Catalog Number:
KL8-H52H3-100ug
Alternative Catalog Number:
ABS-KL8-H52H3-100UG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Kallikrein 8 (KLK8), also known as Neuropsin, PRSS19, or TADG14, is a member of the human kallikreinrelated peptidase family located on chromosome 19. It is a secreted serine protease with strong expression in the hippocampus, where it regulates synaptic plasticity, learning, and memory through cleavage of extracellular matrix proteins and neural adhesion molecules. KLK8 has also been implicated in skin physiology, including keratinocyte proliferation and desquamation. Abnormal expression of KLK8 has been reported in several cancers, such as ovarian and colorectal cancer, making it a potential biomarker and therapeutic target2. - Proteine/Peptide
