Biotinylated Human LAG-3 / CD223 Protein, Fc,Avitag(TM) (MALS verified)

Catalog Number: ABS-LA3-H82FB-25UG
Article Name: Biotinylated Human LAG-3 / CD223 Protein, Fc,Avitag(TM) (MALS verified)
Biozol Catalog Number: ABS-LA3-H82FB-25UG
Supplier Catalog Number: LA3-H82Fb-25ug
Alternative Catalog Number: ABS-LA3-H82FB-25UG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Biotin
Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Iglike domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA classII antigens. - Proteine/Peptide
Molecular Weight: 75.0 kDa
Tag: C-Fc & C-Avi
NCBI: 18627
Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
Purity: 95%
Form: Powder
Target: LAG-3
Immobilized Anti-Human LAG3 MAb, Human IgG1 at 2 µg/mL (100 µL/well) can bind Biotinylated Human LAG-3, Fc,Avitag (Cat. No. LA3-H82Fb) with a linear range of 0.1-3 ng/mL (QC tested).
Serial dilutions of Anti-LAG3, Neutralizing Antibody were added into Human FGL1, His Tag (Cat. No. FG1-H52Hy): Biotinylated Human LAG-3, Fc,Avitag (Cat. No. LA3-H82Fb) binding reactions. The half maximal inhibitory concentration (IC50) is 0.16695 µg/mL (Routinely tested).
Biotinylated Human LAG-3, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.