Human CD4 / LEU3 Protein, His Tag (MALS verified), Unconjugated

Catalog Number: ABS-LE3-H5228-1MG
Article Name: Human CD4 / LEU3 Protein, His Tag (MALS verified), Unconjugated
Biozol Catalog Number: ABS-LE3-H5228-1MG
Supplier Catalog Number: LE3-H5228-1mg
Alternative Catalog Number: ABS-LE3-H5228-1MG
Manufacturer: AcroBiosystems
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Conjugation: Unconjugated
Tcell surface glycoprotein CD4 is also known as Tcell surface antigen T4/Leu3. CD4 contains three Iglike C2type (immunoglobulinlike) domains and one Iglike Vtype (immunoglobulinlike) domain. CD4 is accessory protein for MHC classII antigen/Tcell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIVinfected patients. - Proteine/Peptide
Molecular Weight: 41.51 kDa
Tag: C-6*His
NCBI: 01730
Buffer: PBS, pH7.4
Purity: 90%
Form: Powder
Target: CD4
Immobilized Ibalizumab at 1 µg/mL (100 µL/well) can bind Human CD4, His Tag (Cat. No. LE3-H5228) with a linear range of 0.8-6 ng/mL (QC tested).
Immobilized Human CD4, His Tag (Cat. No. LE3-H5228) at 1 µg/mL (100 µL/well) can bind Ibalizumab with a linear range of 0.2-13 ng/mL (Routinely tested).
Human CD4, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.