Human Legumain Protein, His Tag (active enzyme), Unconjugated 1 mg

Product Overview

• Article Name: Human Legumain Protein, His Tag (active enzyme), Unconjugated 1 mg
• Biozol Catalog Number: ABS-LEN-H52H3-1MG
• Supplier Catalog Number: LEN-H52H3-1mg
• Alternative Catalog Number: ABS-LEN-H52H3-1MG
• Manufacturer: AcroBiosystems
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Unconjugated

Product Description

This gene encodes a member of the cysteine peptidase family C13 that plays an important role in the endosome/lysosomal degradation system. The encoded inactive preproprotein undergoes autocatalytic removal of the Cterminal inhibitory propeptide to generate the active endopeptidase that cleaves protein substrates on the Cterminal side of asparagine residues. Mice lacking the encoded protein exhibit defects in the lysosomal processing of proteins resulting in their accumulation in the lysosomes, and develop symptoms resembling hemophagocytic lymphohistiocytosis. - Proteine/Peptide

Product Properties

• Molecular Weight: 49.5 kDa
• Tag: C-10*His
• NCBI: 99538
• Buffer: 20 mM Tris, 50 mM NaCl, PH7.5
• Purity: 95%
• Form: Liquid
• Target: Legumain

Images

Human Legumain Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.