CD antigen CD58 is also known as Lymphocyte functionassociated antigen 3 (LFA3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the Tlymphocyte CD2 glycoprotein, which binds to CD2 (LFA2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA3/CD2 interaction may prime response by both the CD2+ and LFA3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis. - Proteine/Peptide
Immobilized Human CD58, His Tag (Cat. No. LF3-H5225) at 10 µg/mL (100 µL/well) can bind Human CD2, Fc Tag (Cat. No. CD2-H5258) with a linear range of 5-78 ng/mL (QC tested).
Human CD58, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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